Hepatoprotective Potential of Herbal Plants and Identifying Important Representatives of Phytoconstituents used for the Treatment of Hepatic Diseases: A Review
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Received 04 November 2025
Revised 20 November 2025
Accepted 29 November 2025
Available Online 31 December 2025
Abstract
The liver is a vital organ of paramount importance involved in maintaining metabolic functions and detoxifying the exogenous and endogenous challenges like xenobiotics, drugs, viral infections and chronic alcoholism. Despite the continuous and rapid advances in modern medicine, liver dysfunction is still a worldwide health problem. Thus, exploring more therapeutic alternatives without severe undesirable side effects is necessary, and medicinal plants should be utilized and reevaluated because of their abundant resources. There has been increasing interest in the exploration on flavonoids from plant sources because of their multipurpose health benefits stated in numerous epidemiological studies. Subsequently flavonoids are directly associated with human dietary components and health, there is a need to evaluate the structure and function relationship. Flavonoids aid in combating oxidative stress and act as growth regulators. For pharmaceutical purposes, cost effective bulk production of different types of flavonoids has been made promising with the help of microbial biotechnology. This review highlights the hepatoprotective potential of flavonoids and their beneficial roles in human health.
Keywords
Flavonoids, Hepatoprotective activity, Liver, Alcohol, Hepatitis, Hepatic diseases
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This is an open access article under the CC BY license .
https://creativecommons.org/licenses/by/4.0/Copyright
© 2025 The Author. Published by Pharmadesc Spectrum
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